System Requirements Guide : Supported Operating Systems

Supported Operating Systems
Xinet Server and Xinet Portal
Note: As of version 18.1, we have added support to run the Xinet Server on Virtual Machines hosted on VMware ESXi Hypervisors.
The Xinet hardware ID, a necessary variable to generate a Xinet license string, is based on hardware specific information and will change depending on what hardware changes are done to a particular machine. If VMware is used as a hypervisor with Xinet installed on a guest OS, it is important to keep the MAC address of the network interface consistent. Any RAM or CPU changes or moving of a VM with the Xinet server installed on it, will not affect the Xinet hardware ID. For more details in formation on how to maintain your MAC address, see Licensing and Hardware IDs.
Client Operating Systems
Note: Xinet 19.1.x will be the last version of Xinet to support OS X 10.8 Mountain Lion and Mac OS X 10.9 Mavericks as a client.